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Pyrrolidone Carboxylic Acid Copper (Copper PCA)

Pyrrolidone Carboxylic Acid Copper (Copper PCA)

INCI Name:Copper PCA
CAS Number:15454-74-7
Assay: ≥98%
Loss on Drying: ≤2.0%
Heavy Metals: ≤10 ppm
Microbiological Standards: Compliant
Solubility: Water‑soluble.
pH Compatibility: 5.0–7.0
Shelf Life: 2 years (proper storage)
Packaging: 1 kg/bag; 25 kg/drum.
Molecular Formula:C₁₀H₁₂CuN₂O₆
Appearance:white powder
Store in a sealed container: Inert atmosphere,Room Temperature.
Storage: Sealed container, inert atmosphere, room temperature; dry, cool, well‑ventilated.

Description

Products Description

High Purity Copper PCA CAS 15454-74-7 Blue Green Crystalline Powder Pyrrolidone Carboxylic Acid Copper Cosmetic Active Raw Material

 

Copper PCA (Copper Pyrrolidone Carboxylate) is a high‑efficiency cosmetic active ingredient combining natural moisturizing factor PCA and essential trace element copper. It delivers superior antioxidant, repairing, anti‑aging, oil‑controlling, and soothing properties, widely used in high‑end skincare, hair care, and after‑sun products.

Copper PCA is a water-soluble bidentate chelate complex formed via coordinate bonding between divalent copper ion (Cu²⁺) and two molecules of L-Pyrrolidone-5-Carboxylic Acid(PCA, endogenous natural moisturizing factor of human stratum corneum). Its in-vitro & in-vivo biological efficacy derives from two core structural components with independent synergistic biochemical mechanisms:

Technical Specification

 

Test Item Quantified Standard Index Detection Test Method
Main Content(Copper PCA on dry base) ≥98.0 % HPLC High Performance Liquid Chromatography
Loss on Drying ≤2.00 % Vacuum Oven Gravimetric Test
1% Aqueous Solution pH(25℃) 5.0 ~7.0 Digital pH Meter
Total Heavy Metal(Pb+As+Cd+Hg) ≤10 ppm ICP-MS Inductively Coupled Plasma Mass Spectrometry
Arsenic(As) ≤1.0 ppm Hydride Generation AAS
Lead(Pb) ≤3.0 ppm Atomic Absorption Spectrometry
Total Aerobic Microbial Count ≤100 CFU/g USP Plate Count Method
Yeast & Mold ≤10 CFU/g Dilution Coating Count
Residual Organic Solvent <300 ppm GC Gas Chromatography
Water Insoluble Impurity ≤0.10 % Gravimetric Filtration
Free Copper Ion Content ≤0.3% Complexometric Titration

 

 

Product Application

01.

Color enhancer

Copper pyrrolidone carboxylate significantly enhances the color rendering effect of dyes or pigments on the skin by complexing with nitrogen-containing water-soluble small molecules such as amino acids, urea, etc. The ratio range is 30:1 to 3:200 (copper pyrrolidone carboxylate: water-soluble nitrogen-containing small molecule).

02.

Application of external dosage forms

Swertia sinensis bitter glycoside has a promoting effect on hair growth. Japanese research has shown that it can effectively stimulate hair follicles and is suitable for use in hair growth products to help improve hair loss problems.

03.

Others

1. Helps repair damage to the skin's protective barrier
2. Provide immediate refreshing hydration
3. Improve skin elasticity and firmness
4. Enhance the glossiness and radiance of the skin
5. Suitable for sunburn/erythema.

Why Choose Us

  1. Controlled High-Purity Production Process: Adopt synthetic chelation + recrystallization purification technology; online HPLC real-time testing per production batch to guarantee finished Copper PCA ≥98% assay, strictly control free copper ion & heavy metal exceeding specification limits.
  2. Complete Global Document Matching Service: Synchronously deliver batch COA, GHS SDS and third-party CNAS test report for every shipment; provide optional REACH/CosIng/HALAL/KOSHER documents to support global customs clearance and buyer factory incoming QC inspection.
  3. Diversified Custom Packaging Solution: Available specification: 1kg nitrogen-sealed aluminum foil bag, 25kg food-grade HDPE drum; customized 50g/100g small trial sample packaging for laboratory formulation test, all packages avoid moisture absorption & light-induced decomposition during long-distance sea/air transportation.
  4. Stable Inventory & Fast Delivery Cycle: Annual stable production output over 30 tons high-purity Copper PCA; conventional bulk goods stocked in warehouse, free sample dispatched within 2 working days after application; bulk order lead time controlled within 5~7 working days after deposit confirmation.
  5. Professional Formulation Technical Support: Provide dosage matching data, pH compatibility scheme and synergistic collocation suggestion with Zinc PCA, Hyaluronic Acid & Vitamin E; assist customers in finished product stability verification test to reduce formula development failure risk.

Full Stock 

affordable price

Professional Team

advanced technology

Frequently Asked Questions

What core chemical structure makes Copper PCA stable in cosmetic pH5.0~7.0 aqueous formula?

 

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Copper PCA forms stable coordinate chelate via Cu²⁺ and two PCA carboxylate groups; the chelate bond prevents rapid copper dissociation under neutral-weak acid environment, avoiding precipitation and loss of biological activity in conventional cosmetic systems.

What is the maximum legal usage percentage of Copper PCA in EU leave-on skincare per CosIng regulation?

 

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EU CosIng sets upper safe limit at 1.0% w/w for leave-on cosmetic products; formulation above 1% needs finished human skin patch safety certification before mass production.

How does Copper PCA achieve dual effects of moisturization and antioxidant on skin layer?

 

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Undissociated PCA ligand provides humectation via polar water-binding groups; slowly released Cu²⁺ activates cutaneous SOD enzyme to eliminate ROS free radicals, realizing two independent biochemical functions from single ingredient.

Can Copper PCA be compounded with Zinc PCA and Hyaluronic Acid in the same cosmetic formula?

 

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Verified formulation test shows excellent compatibility at processing temperature below 40℃; no precipitation or chemical degradation, meanwhile generates synergistic sebum-control & barrier-repair efficacy.

What's proper storage condition to reach 24-month shelf life of bulk Copper PCA?

 

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Keep package sealed with nitrogen filling, store at 10~25℃ cool dry warehouse away from sunlight and iron/copper containers; once unpacked, finish consumption within 3 months to prevent deliquescence.

delivery and shipping service

High Purity Copper PCA CAS 15454-74-7 Blue Green Crystalline Powder Pyrrolidone Carboxylic Acid Copper Cosmetic Active Raw Material

01.Packaging and service

Storage: Store in a dry, cool, and well-ventilated place.

Packaging: 1 kg/bag, 25 kg/drum

Delivery Time: 7 days after order placement

02.Delivery Methods

1.Express Delivery
3-5 days for shipments under 100 kg
Door-to-door service

2.Ocean Freight
Over 300 kg: Approximately 30 days. Port-to-port service requires a professional customs clearance agent.

3.Air Freight
100kg-1000kg, 5-7 days
Airport-to-airport service, requires a professional customs clearance agent

High Purity Copper PCA CAS 15454-74-7 Blue Green Crystalline Powder Pyrrolidone Carboxylic Acid Copper Cosmetic Active Raw Material

Pyrrolidone Carboxylic Acid Copper (Copper PCA)
Send inquiry or contact us to get free sample, and learn more details about it.

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