Products Description
L‑Ergothioneine is a rare, naturally occurring amino acid and high‑efficiency antioxidant widely used in high‑end skincare and cosmetic formulations. It acts as a strong free‑radical scavenger to protect skin cells from oxidative stress, UV damage, and environmental aggressors. With excellent stability and skin compatibility, L‑Ergothioneine provides multiple benefits including antioxidant protection, long‑lasting moisturization, soothing inflammation, and visible anti‑aging effects. It is widely applied in anti‑aging serums, moisturizers, soothing creams, brightening products, and sun‑care formulas.
Technical Specification
| Item | Standard Value | Test Method |
|---|---|---|
| CAS No. | 497-30-3 | International Chemical Database |
| INCI Name | Ergothioneine | Cosmetic INCI Standard |
| Molecular Formula | C₉H₁₅N₃O₂S | Chemical Analysis |
| Molecular Weight | 229.30 g/mol | Calculation & Detection |
| Appearance | Uniform white crystalline powder | Visual Inspection |
| Purity | ≥99.0% | HPLC (High Performance Liquid Chromatography) |
| Water Content | ≤1.0% | Karl Fischer Titration |
| pH Value (50 mg/mL, 20℃) | 5.5 ~ 7.0 | pH Meter Detection |
| Heavy Metal (Pb) | ≤1 ppm | ICP-MS |
| Arsenic (As) | ≤1 ppm | ICP-MS |
| Total Microorganism | ≤100 CFU/g | Microbial Culture |
| Solubility | Fully soluble in deionized water | Solubility Test |
| Storage Stability | Stable under normal temperature & physiological pH | Accelerated Stability Test |
| Shelf Life | 24 months (sealed & standard storage) | Long-term Stability Observation |
| Mesh Size | 100% pass 50-mesh sieve | Sieve Test |
Product Application
Powerful Antioxidant
Neutralizes reactive oxygen species (ROS) and free radicals, reduces oxidative damage, and supports skin's natural defense system.
Long‑Lasting Moisturizing
Enhances skin hydration, reduces dryness, roughness, and flaking, and diminishes fine lines caused by dehydration.
Anti‑Inflammatory & Soothing
Calms redness, sensitivity, and irritation; supports skin barrier repair and comfort.
Anti‑Aging & Firming
Protects collagen and elastin, reduces wrinkles and pigmentation, improves skin elasticity and texture.
Safety Profile
Safety Performance Data
- Skin Irritation: Non-irritating to human skin; no erythema, edema or pruritus in 24h/48h/72h patch tests on normal and sensitive skin.
- Eye Irritation: Non-irritating to eye mucosa under cosmetic application concentration.
- Sensitization: No skin sensitization reaction in repeated contact sensitization tests.
- Phototoxicity & Photoallergy: Negative results in phototoxicity and photoallergy tests, no adverse reaction under UV irradiation.
- Acute Toxicity: Oral and dermal acute toxicity LD50 > 2000 mg/kg, belonging to non-toxic grade.
- Genotoxicity: All genotoxicity test results are negative, no potential genetic risk.
- Application Concentration Safety: Within the cosmetic recommended dosage (0.1% - 2.0%), no toxic or side effects to human skin and body.
Authoritative Safety Certificates & Documents (Available for Delivery)
We provide complete traceable certificates and test reports for customs clearance, cosmetic filing and quality inspection:
- COA (Certificate of Analysis): Batch-by-batch full ingredient detection report, with complete quantitative data of all technical indicators.
- HPLC Test Report: Purity detection original report of L-Ergothioneine.
- MSDS/SDS (Material Safety Data Sheet): Global universal chemical safety data sheet, compliant with GHS standard.
- SGS Third-Party Test Report: Heavy metals, microorganisms and skin safety inspection report issued by SGS.
- Regulatory Compliance Certificate: Compliant with China Cosmetic Raw Material Directory, US FDA GRAS certification, EU cosmetic raw material access standard.
- Production Qualification: ISO 9001 Quality Management System Certificate, production process flow chart.
Why Choose our Company
- High purity ≥99% (HPLC), stable quality
- Full stock, fast lead time (7 days)
- Competitive factory price
- Professional R&D and technical support
- Strict quality control from raw material to finished product
- Safe, non‑irritating, suitable for cosmetic formulations
- Flexible packaging and reliable global logistics
Full Stock
affordable price
Professional Team
advanced technology
delivery and shipping service
Storage: Store in a dry, cool, and well-ventilated place.
Packaging: 1 kg/bag, 25 kg/drum
Delivery Time: 7 days after order placement
1.Express Delivery
3-5 days for shipments under 100 kg
Door-to-door service
2.Ocean Freight
Over 300 kg: Approximately 30 days. Port-to-port service requires a professional customs clearance agent.
3.Air Freight
100kg-1000kg, 5-7 days
Airport-to-airport service, requires a professional customs clearance agent
Frequently Asked Questions
Is L‑Ergothioneine suitable for sensitive skin?
-
Yes. L‑Ergothioneine is a skin‑friendly, non‑irritating, natural amino acid antioxidant. It has anti‑inflammatory and soothing properties, making it safe for sensitive, reactive, and post‑procedure skin.
What is the recommended dosage in cosmetics?
-
Typical recommended concentration is 0.1%–2.0%. It can be used in serums, creams, lotions, masks, and sunscreens. Exact dosage depends on formulation design and efficacy target.
How stable is L‑Ergothioneine during production and storage?
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It shows excellent stability at room temperature and physiological pH, with low auto‑oxidation. Avoid strong acids, strong alkalis, and prolonged high‑heat processing to maintain activity.
Can L‑Ergothioneine be used with other antioxidants?
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Yes. It works synergistically with vitamin C, vitamin E, ferulic acid, glutathione, etc., to enhance overall antioxidant, brightening, and anti‑aging performance.
What documents and certificates are provided?
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We supply COA, HPLC test report, MSDS, specification sheet, flow chart, and other necessary documents for customs clearance and regulatory filing.
Send inquiry or contact us to get free sample, and learn more details about it.
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