What is d-alpha-Tocopheryl Succinate?

d-alpha-Tocopheryl Succinate, also known as Vitamin E Succinate, is a premium esterified natural vitamin E antioxidant widely used in global cosmetic, skincare and personal care formulations. With CAS No.4345-18-2, this white powder features superior thermal & pH stability compared with free alpha-tocopherol, low skin irritation and excellent compatibility with oil, emulsion and powder cosmetic systems. Our factory supplies HPLC-tested 98% high-purity raw material that complies with EU & FDA cosmetic regulations, supporting bulk wholesale, custom packaging and full compliance documents for worldwide distributors and skincare manufacturers.
Full Technical Specifications & Test Standards
| Test Item | Specification | Test Method |
|---|---|---|
| d-alpha-Tocopheryl Succinate Content | ≥98.0% | HPLC |
| Specific Rotation [α]D²⁰ | +24.0° ~ +28.0° | Polarimeter |
| Melting Point | 70 ℃ ~ 78 ℃ | Capillary Method |
| Loss on Drying | ≤0.50% | GB/USP Standard |
| Residue on Ignition | ≤0.10% | Gravimetric Method |
| Heavy Metals (as Pb) | ≤10 ppm | AAS |
| Arsenic (As) | ≤2 ppm | AAS |
| Lead (Pb) | ≤2 ppm | AAS |
| Cadmium (Cd) | ≤1 ppm | AAS |
| Mercury (Hg) | ≤0.1 ppm | AAS |
| Total Aerobic Microorganisms | ≤100 CFU/g | Microbiological Test |
| Yeast & Mold | ≤10 CFU/g | Microbiological Test |
| Pathogenic Bacteria | Negative | Microbiological Test |
Core Benefits & Cosmetic Application Fields
Powerful Antioxidant & Anti-Photoaging Formula Ingredient
As a stable lipid-soluble antioxidant, d-alpha-Tocopheryl Succinate effectively eliminates skin free radicals, blocks lipid peroxidation and protects cell membranes from UV damage. It is a core active raw material for after-sun repair cream, anti-photoaging lotion and antioxidant serums.
Anti-Wrinkle & Skin Firming Active
It prevents oxidative degradation of collagen and elastin fibers, maintains skin elasticity, reduces fine lines and sagging issues, ideal for mature anti-aging skincare lines.
Skin Brightening & Dark Spot Inhibitor
Restrains tyrosinase activity and reduces melanin accumulation to balance uneven skin tone, commonly added in brightening essence and spot-fading cream.
Skin Barrier Repair & Moisturizing Agent
Strengthens stratum corneum moisture-locking capacity, relieves dry, rough and flaky skin, suitable for sensitive skin repair moisturizers.
Complete Safety Toxicology Profile
- Acute Toxicity: Oral LD₅₀ (rat) > 20000 mg/kg, classified as practically non-toxic via oral administration.
- Skin Irritation: Standard rabbit skin irritation test: Non-irritating to intact and damaged skin under normal use concentration.
- Eye Irritation: Rabbit eye irritation test: Slight transient irritation at raw material concentration; no persistent damage when diluted per application ratio.
- Sensitization: Repeated skin sensitization test (guinea pig): No allergic sensitization reaction observed.
- Genotoxicity: Ames test and chromosome aberration test: No genotoxic potential detected.
- Stability & Storage: Stable under normal temperature and sealed storage; avoid strong light, high temperature and strong oxidants. No decomposition and harmful substance generation within shelf life.
- Use Restriction: Not recommended for use on damaged, inflamed skin or mucosa in high concentration.
Why Choose Our d-alpha-Tocopheryl Succinate
Our d-alpha-Tocopheryl Succinate main content reaches ≥98% tested by HPLC per batch, consistent indexes and low impurity heavy metal control, stable mass supply for long-term OEM skincare manufacturers.
2. Full Global Compliance Documents
Every shipment supports complete COA, MSDS, heavy metal & microbiology test reports, meeting EU CosIng, FDA and international cosmetic raw material access standards.
3. Strict Standardized QC System
GMP-level production workshop, multi-stage inspection from raw material input to finished product delivery, zero unqualified goods outflow.
4. Professional Formulation Technical Support
Our cosmetic R&D team provides customized dosage guidance, formula matching solutions and application suggestions for different skincare systems.
5. Flexible Packaging & Stable Bulk Supply
Large-scale production capacity supports bulk long-term orders; customizable 1kg bag / 25kg drum packaging and third-party testing services as requested.
6. Global Logistics & Low MOQ Sample Service
Fast 7-day production lead time, door-to-door express, air & sea freight options for worldwide buyers; free samples available for formula trial.
Full Stock
affordable price
Professional Team
advanced technology
Packaging, Storage & Global Shipping Solutions

- Standard package: 1kg aluminum foil bag, 25kg fiber drum.
- Storage requirement: Keep sealed in cool, dry, ventilated warehouse without direct sunlight or high temperature; shelf life reaches 24 months under proper storage.
- Lead time: 7 working days after deposit confirmation.
1. Express Delivery (≤100kg): 3-5 days door-to-door service, suitable for lab sample testing orders.
2. Air Freight (100kg-1000kg): 5-7 days airport-to-airport, support customs clearance document assistance.
3. Ocean Freight (≥300kg): Around 30 days port-to-port, cost-effective for large bulk factory orders.

Frequently Asked Questions About Vitamin E Succinate
What is the difference between d-alpha-Tocopheryl Succinate and free alpha-tocopherol?
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Vitamin E Succinate is ester-protected vitamin E with outstanding stability against heat, light and oxidation. It avoids formula yellowing & deterioration, delivers milder skin irritation and better dispersibility in cosmetic formulas than free tocopherol.
Is d-alpha-Tocopheryl Succinate safe for sensitive & acne-prone skin products?
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Yes. It has low comedogenicity and passes rabbit skin irritation & guinea pig sensitization tests, non-allergic under recommended dosage 0.5%-1%.
What is the recommended addition dosage in cosmetics?
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Standard effective dosage range: 0.5% to 1% for most skincare creams, serums and emulsions. Excessive addition brings no extra performance improvement.
Can this raw material compound with Vitamin C, Retinol and peptide actives?
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Absolutely. It creates synergistic antioxidant effects and stabilizes easily oxidized actives like L-Ascorbic Acid and retinol to extend formula shelf life.
How to store d-alpha-Tocopheryl Succinate to retain its activity?
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Store in airtight containers, cool dry environment away from light, heat and oxidants. Inert gas filling is recommended for long-term bulk storage, valid for 24 months.

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