Products Description
γ-Polyglutamic Acid (γ-PGA) is a water-soluble anionic homo-polymer generated via microbial fermentation of L-glutamic acid monomers with amide linkage on γ-carboxyl site of glutamic acid molecular structure. Its linear polypeptide chain carries abundant free carboxylate groups distributed evenly along molecular backbone, enabling two core physical-chemical working mechanisms when incorporated into cosmetic aqueous formulations.
Hydration retention mechanism: Free carboxylate groups combine with ambient free water molecules via hydrogen bonding and dipole interaction to form stable bound-water complex, lowering transepidermal water loss (TEWL) by constructing continuous hydrated film on stratum corneum surface without disrupting intercellular lipid bilayer arrangement of epidermis.
Cuticle conditioning mechanism: Anionic molecular chain adheres to positively charged keratin amino residues on aged cuticle via electrostatic attraction, filling micro-cracks between exfoliating corneocytes to smooth uneven skin surface physically, no chemical denaturation to native keratin protein structure. This fermentation-derived polymer is free from petrochemical synthetic feedstock, classified as natural-origin cosmetic functional raw material complying with global cosmetic ingredient restriction specifications. The cosmetic-grade variant is refined through ultrafiltration, decolorization and microbial removal processing to eliminate fermentation residual impurities, matching cosmetic formulation hygiene thresholds.
Product Functions
Extreme Long-Lasting Hydration
Creates a breathable moisture-locking film on skin surface, effectively reduces water evaporation, and delivers continuous hydration for all skin types including dry, oily and combination skin.
Brightening & Even Skin Tone
Helps inhibit melanin formation, lighten dark spots and dull complexion, and supports brightening recovery for skin after beauty and optical treatments.
Anti-Wrinkle & Firming Care
Boosts skin elasticity and collagen activity, softens fine lines and wrinkles, fights free radical damage, and slows down skin aging.
Active Ingredient Synergy
Forms a slow-release system to enhance absorption and utilization of skincare actives, making formula more effective and longer-lasting.
Why Choose Us
- Customizable molecular weight production: We adjust γ-PGA molecular chain length ranging from 500kDa to 3MDa based on clients' finished cosmetic formulation requirement, produce tailor-made batches instead of fixed single specification to match different product system (aqueous/hydrogel/cream base).
- Independent microbial fermentation workshop: Full production line from strain cultivation, fermentation, ultrafiltration refining to decolorization is self-operated, controlling residual monomer and impurity content stably to meet consistent COA test data per batch; each shipment comes with batch-specific Certificate of Analysis.
- Complete regulatory document system: Pre-prepared REACH compliant SDS, third-party CNAS lab safety test report, batch COA available for all cosmetic-grade γ-PGA orders, supporting customers' domestic and overseas cosmetic filing work in EU, USA, Southeast Asia market.
- Flexible order scale: Support lab small sample order (10g~1kg for formulation trial) and industrial bulk pallet order (25kg/drum), sample delivery within 3 working days for global customers.
- Strict pre-shipment double inspection: Raw material is tested twice (in-house QC lab + third-party random spot check) before outbound shipment to avoid batch parameter deviation.
Full Stock
affordable price
Professional Team
advanced technology
delivery and shipping service
Storage: Store in a dry, cool, and well-ventilated place.
Packaging: 1 kg/bag, 25 kg/drum
Delivery Time: 7 days after order placement
1.Express Delivery
3-5 days for shipments under 100 kg
Door-to-door service
2.Ocean Freight
Over 300 kg: Approximately 30 days. Port-to-port service requires a professional customs clearance agent.
3.Air Freight
100kg-1000kg, 5-7 days
Airport-to-airport service, requires a professional customs clearance agent
Frequently Asked Questions
What is the INCI name and CAS number of cosmetic grade γ-Polyglutamic Acid?
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Its official INCI Name is Polyglutamic Acid, corresponding CAS No. 25513-46-6, the data is compliant with global cosmetic ingredient registration database CosIng and IECIC.
What is the recommended addition amount of γ-PGA in facial serum formulation?
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The standard recommended dosage is 0.1% to 2.0% by weight for leave-on facial serum; customers can do small-scale formulation trial to adjust dosage according to finished product texture demand.
Can cosmetic grade γ-PGA be dissolved directly in high-concentration alcohol cosmetic formula?
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No, γ-Polyglutamic Acid is insoluble in ethanol and high alcohol solution over 45% alcohol content, it will precipitate out; we suggest adding this raw material into aqueous phase before mixing with alcohol phase.
Is your cosmetic γ-PGA available with SDS safety document?
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Yes, GHS & REACH compliant SDS file is supplied free for every order, scanned PDF file will be attached together with proforma invoice after order confirmation.
Can I customize different molecular weight of γ-Polyglutamic Acid?
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Available, our factory supports customized MW from 500,000 Da to 3,000,000 Da, minimum customized batch quantity will be informed according to your target parameter.
Send inquiry or contact us to get free sample, and learn more details about it.
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