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3-O-Ethyl-L-Ascorbic Acid

Product Name: 3-O-Ethyl-L-Ascorbic Acid
INCI Name: 3-O-Ethyl Ascorbic Acid
Cas no.:86404-04-8
Molecular Formula:C8H12O6
Molecular Weight:204.18 g/mol
Appearance:White to off-white crystalline powder
Purity:≥98% (Cosmetic Grade)
Stability:Stable at pH 5–7; resistant to light & heat.
Solubility:Water-soluble, enhanced lipid solubility.
Storage:Sealed, inert atmosphere, room temperature, dry & cool.
Packaging:1 kg/bag; 25 kg/drum.
Lead Time:7 days after order.

Description

Products Description

3-O-Ethyl-L-Ascorbic Acid white crystalline powder cosmetic raw material

 

3-O-Ethyl-L-Ascorbic Acid is a stable ethylated vitamin C derivative widely used in cosmetics, food, and pharmaceutical fields. Compared with pure vitamin C, it features stronger stability, better transdermal absorption, and higher antioxidant activity, making it a core active ingredient for high‑end brightening, anti‑aging, and repairing formulations.

Technical Specification

 

Test Item Standard Specification Test Method
Molecular Formula C₈H₁₂O₆ Elemental Analysis
Molecular Weight 204.18 g/mol Mass Spectrometry
Appearance White to off-white crystalline powder Visual Inspection
Purity (HPLC) ≥98.0% (Cosmetic Grade) High Performance Liquid Chromatography
Water Solubility ≥778 g/L (20℃) Gravimetric Method
pH Value (1% Aqueous Solution) 5.0 – 7.0 pH Meter
Melting Point 112℃ Melting Point Tester
Storage Stability (pH 5–7) No discoloration & inactivation within 12 months (room temperature) Accelerated Stability Test
Light & Heat Resistance No obvious degradation after 48h under 45℃ & UV irradiation Environmental Simulation Test
Loss on Drying ≤1.0% Drying Method
Heavy Metal (Pb/As/Hg/Cd) Compliant with EU Cosmetic Raw Material Standards Atomic Absorption Spectroscopy

 

Safety Profile

 

Safety Evaluation & Toxicological Data

  • Skin Irritation: Non-irritating to normal skin and sensitive skin within cosmetic conventional dosage range; no cumulative irritation in long-term topical use .
  • Eye Irritation: Slightly irritating to eyes in pure state; finished cosmetics with conventional concentration will not cause eye irritation .
  • Allergenicity: Low allergy risk, not listed in EWG restricted allergen ingredients .
  • Authority Assessment: Certified safe by CIR (Cosmetic Ingredient Review) and SCCS. Maximum safe dosage for leave-on cosmetic products: ≤10%; maximum safe dosage for rinse-off cosmetic products: ≤10% .
  • DPPH Radical Scavenging IC₅₀: 0.032 g/L, high antioxidant activity with low toxic risk .

Available Safety & Compliance Certificates 

  • SDS (Safety Data Sheet) – Full version in English, available for download & customs declaration
  • COSMETIC GMP Certificate
  • EU Cosmetic Regulation (EC 1223/2009) Compliance Report
  • CIR Safety Assessment Report
  • Heavy Metal & Microorganism Test Report
  • Non-animal cruelty certification 

 

Product Application

01.

Powerful Antioxidant & Anti‑Aging

Scavenges free radicals at 1.8× the efficiency of L‑ascorbic acid, activates fibroblasts, boosts collagen synthesis by up to 35% in vitro, improves skin elasticity, and reduces fine lines and wrinkles.

02.

Skin Whitening & Spot Fading

Inhibits tyrosinase activity, blocks melanin synthesis, and reduces existing melanin. Clinical tests show a 23% reduction in dark spot area after 8 weeks of using a 2% solution.

03.

UV Damage Protection & Repair

Neutralizes UV‑induced free radicals, reduces sunburn cells, and provides dual antioxidant + anti‑inflammatory protection for daily sun‑repair routines.

04.

Excellent Stability & Penetration

Ethyl modification improves lipid solubility and skin permeability; stable in pH 5–7, less affected by light and heat, easy to formulate and store.

Everything You Need to Know

 

Is 3-O-Ethyl-L-Ascorbic Acid more stable than pure vitamin C?

A: Yes. The ethyl group protects the molecule from oxidation, light, and heat. It remains stable in pH 5–7 without easy yellowing or inactivation, greatly extending shelf life compared to L‑ascorbic acid.

Can 3-O-Ethyl-L-Ascorbic Acid really penetrate skin and work?

A: Yes. Its amphiphilic structure improves transdermal absorption. It converts to active vitamin C inside skin layers to deliver brightening, antioxidant, and collagen‑boosting effects.

What concentration is recommended for formulations?

A: Common effective range is 1%–5%. For spot fading and anti‑aging, 2%–5% is widely used; higher concentrations up to 10% are safe and non‑irritating in professional formulas.

Is it suitable for sensitive skin?

A: Yes. It is milder than pure vitamin C, non‑irritating at cosmetic concentrations, and compatible with most skin types including sensitive skin.

Why Choose our Company

  • Stable supply & strong R&D capacity
  • Strict quality control from raw material to finished product
  • Competitive factory wholesale price
  • Free samples & professional technical support
  • Fast delivery & full after‑sales service

Full Stock 

affordable price

Professional Team

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delivery and shipping service

Stable vitamin C derivative 3-O-Ethyl-L-Ascorbic Acid CAS 86404-04-8

01.Packaging and service

Storage: Store in a dry, cool, and well-ventilated place.

Packaging: 1 kg/bag, 25 kg/drum

Delivery Time: 7 days after order placement

02.Delivery Methods

1.Express Delivery
3-5 days for shipments under 100 kg
Door-to-door service

2.Ocean Freight
Over 300 kg: Approximately 30 days. Port-to-port service requires a professional customs clearance agent.

3.Air Freight
100kg-1000kg, 5-7 days
Airport-to-airport service, requires a professional customs clearance agent

3-O-Ethyl-L-Ascorbic Acid whitening anti-aging skincare application

3-O-Ethyl-L-Ascorbic Acid 25kg drum packaging wholesale
Send inquiry or contact us to get free sample, and learn more details about it.

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