Hydroxyethyl Urea-Humectant

Hydroxyethyl Urea is a small‑molecule urea derivative with a hydrophilic structure containing one hydroxyl group and two amide groups. It acts as a high‑efficiency humectant and skin/hair conditioning agent via multiple physical and physiological mechanisms.

Hydration Mechanism

1. Hygroscopic Binding Hydroxyethyl Urea forms multiple hydrogen bonds with water molecules, enabling high hygroscopicity. At 36°C, 85% RH equilibrium, its hygroscopic capacity reaches 82% of its own weight, significantly higher than glycerin (≈34%).
2. Stratum Corneum Penetration Low molecular weight allows rapid penetration into the stratum corneum, increasing intercellular water content, reducing TEWL, and relieving dryness, roughness, and scaling.
3. Skin Barrier Support Promotes hydration of keratin and supports the natural moisturizing factor (NMF) network, improving elasticity, smoothness, and long‑term barrier function.
4. Formulation Function Reduces tackiness and improves spreadability without greasiness; stabilizes formulas and enhances sensory properties across leave‑on and rinse‑off systems.
5. Stability & Compatibility Stable over a wide pH range (5.0–9.0); compatible with anionic, nonionic, amphoteric surfactants, humectants, and active ingredients.

• Acute Oral Toxicity (rat): LD₅₀ >3473 mg/kg bw → practically non‑toxic.
• Acute Dermal Toxicity (rabbit): LD₅₀ >3473 mg/kg bw → low acute risk.
• Skin Irritation: Non‑irritating at cosmetic use concentrations (≤20%); in vitro EpiDerm model negative.
• Eye Irritation: Mild at high concentrations; well‑tolerated in finished formulations.
• Skin Sensitization: Non‑sensitizing in guinea pig maximization tests (GPMT).
• Genotoxicity: Ames test negative; no genotoxic potential reported.
• Carcinogenicity & Reproductive Toxicity: No evidence of carcinogenicity or reproductive/developmental toxicity.
• Regulatory Status:

CIR Expert Panel: safe up to 20.6% in leave‑on products when formulated non‑irritating.

Included in China IECIC (2021), EU CosIng, Australia NICNAS, and Japan NIFC lists.

• GHS Classification: Not classified as hazardous under normal cosmetic handling.

• MSDS (SDS)
• Batch COA (Certificate of Analysis)
• IECIC & EU CosIng Compliance Certificates
• Heavy Metals & Microbial Test Reports
• CIR Safety Assessment Summary

1. Leave‑On Skincare (Serums, Creams, Lotions)

• Use Level: 2%–10% (up to 20% for intensive dry‑skin repair)
• Allowed: All skin types including dry, sensitive, acne‑prone
• Restrictions: For external topical use only; avoid direct eye contact

2. Rinse‑Off Products (Body Wash, Shampoo, Facial Cleanser)

• Use Level: 1%–5%
• Allowed: Daily care, sensitive skin/scalp
• Restrictions: Rinse thoroughly; not for leave‑on

3. Color Cosmetics (Foundation, BB Cream, Concealer)

• Use Level: 0.5%–3%
• Allowed: Liquid, cream, and stick formulas
• Restrictions: Avoid mucous membranes; for external use only

4. Medical Skincare & Barrier Repair

• Use Level: 5%–15%
• Allowed: Dry, atopic‑prone, post‑procedure skin
• Restrictions: Not for open wounds; discontinue if irritation occurs

5. Hair Care (Conditioner, Hair Mask, Leave‑In Treatment)

• Use Level: 1%–8%
• Allowed: Dry, frizzy, color‑treated hair
• Restrictions: Avoid scalp contact in high concentrations

1. Precise Concentration Control Strictly controlled at 48.0%–52.0%, consistent batch‑to‑batch stability for reliable formulation.
2. Superior Humectant Mechanism Higher hygroscopicity than glycerin; fast‑penetrating, non‑sticky, long‑lasting hydration.
3. Wide Compatibility & Stability Compatible with most cosmetic ingredients; stable across pH 5.0–9.0 for versatile formulation.
4. Proven Safety & Compliance Full toxicology dossiers; CIR, EU, China, and global regulatory approvals.
5. Stable Supply & Flexible Packaging 25 kg/drum; 7‑day lead time; air/sea/express shipping worldwide.
6. Professional Technical Support Formulation guidance, stability testing, and regulatory document support.

01.Packaging and service

Storage: Store in a dry, cool, and well-ventilated place.

Packaging: 1 kg/bag, 25 kg/drum

Delivery Time: 7 days after order placement

02.Delivery Methods

1.Express Delivery
3-5 days for shipments under 100 kg
Door-to-door service

2.Ocean Freight
Over 300 kg: Approximately 30 days. Port-to-port service requires a professional customs clearance agent.

3.Air Freight
100kg-1000kg, 5-7 days
Airport-to-airport service, requires a professional customs clearance agent

Send inquiry or contact us to get free sample, and learn more details about it.

Send Inquiry Now

Hot Tags: Hydroxyethyl Urea-Humectant, China Hydroxyethyl Urea-Humectant manufacturers, suppliers, factory, symplocos racemosa extract, energizing ingredients, stinging nettle root powder, chamomile extract for cosmetics, jojoba oil for cosmetics, silk cocoon amino acid skincare ingredient