Product Introduction
L-(+)-Ergothioneine, known as premium cell-targeted antioxidant amino acid for high-end skincare, is exclusively produced via controlled edible mushroom fermentation by Xi'an Dowell Healthy. Unlike chemically synthesized alternatives, our EGT powder retains natural bioactivity without residual synthetic impurities, meeting EU cosmetic safety and CPNP notification standards.
This sulfur-containing imidazole-thione molecule owns a unique biological feature: human skin cells actively absorb it through the OCTN-1 transporter, then concentrate EGT inside mitochondria-the core zone where 90% of skin oxidative damage occurs. It executes multi-layer skin protection through 5 independent synergistic pathways: neutralizing ROS/RNS free radicals, chelating iron & copper metal ions to block Fenton oxidation chain reaction, stabilizing mitochondrial membrane & cellular DNA against photo damage, balancing endogenous antioxidant circulation, and maintaining stable activity under high-temperature cosmetic mixing & long shelf storage.
Visually presented as white to off-white fine crystalline powder, the raw material features complete water solubility, neutral pH property, and perfect compatibility with all water-based, emulsion, gel cosmetic systems. Our batch purity reaches ≥99% tested by HPLC strict detection, with ultra-low heavy metal and microbial limits suitable for sensitive skin, sun care, anti-aging and brightening finished cosmetics. Multiple global authoritative certifications including FDA GRAS, EFSA novel food approval, China IECIC 2021 listing, Kosher, Halal, ISO & Non-GMO certificates fully support cross-border cosmetic brand registration worldwide.
Technical Specification
| Classification Item | Specific Details |
|---|---|
| Production Source | Natural edible mushroom deep liquid fermentation, zero chemical synthesis residue |
| Main Target Cell Receptor | OCTN-1 specific cell transporter for epidermal & mitochondrial uptake |
| Usable Formulation pH Window | pH 3.0 – 9.0, compatible with acidic serum & alkaline cleansing formulas |
| Main Antioxidant Competitive Edge | Outperforms Vitamin C, Glutathione, CoQ10 on thermal stability & blue light neutralization |
| Target Skin Troubles | Photoaging, melanin hyperpigmentation, mitochondrial oxidative damage, sensitive skin redness |
| Standard Sample Specification | 10g / 50g / 100g free lab test samples (buyer covers shipping cost) |
| Core Global Regulatory Certifications | FDA GRAS, EFSA Novel Food, China IECIC 2021, ISO9001, FSSC22000, Kosher, Halal |
| Long-term Storage Suggestion | Sealed vacuum aluminum bag, -20℃ dark storage to extend activity retention cycle |
Application & Recommended Dosage
Core Cosmetic Application Scenarios
- Anti-aging & anti-wrinkle serums, firming face cream, overnight repair mask
- Daily broad-spectrum sunscreen, blue light defense urban repair skincare
- Brightening, spot fading, uneven tone correction essence & ampoule
- Barrier repair lotion, sensitive skin soothing calming toner
- Antioxidant anti-fading hair care essence & scalp care formulas
Suggested Addition Dosage for Finished Cosmetics
0.05% – 1% weight ratio, adjustable based on finished product efficacy positioning:
- Mild daily maintenance skincare: 0.05% – 0.2%
- High-efficiency anti-aging & brightening essence: 0.3% – 0.6%
- Professional medical beauty intensive repair series: 0.7% – 1%
Extended Industrial Application
Beyond cosmetic raw materials, high-purity ergothioneine powder can also be applied in oral antioxidant dietary supplements and functional food raw materials under food-grade production standards.
Why Choose Our Dowell Natural Ergothioneine Powder
- Patented Mushroom Fermentation Production Route
We adopt closed liquid deep fermentation technology from natural golden mushrooms, no chemical synthesis steps, zero harmful solvent residues, fully compliant with EU, US and Asia cosmetic ingredient import rules. Each batch fermentation process is recorded and traceable.
- Stable Ultra-High Purity & Consistent Batch Quality
Every production lot undergoes dual HPLC lab testing before delivery, strictly controlling heavy metal, microbial and moisture indicators; independent quality inspection laboratory ensures no purity fluctuation between bulk orders.
- Over 10 Years Professional Cosmetic Raw Material Export Factory
Xi'an Dowell owns independent GMP standard production workshop, professional foreign trade technical team, rich experience serving global cosmetic OEM brands, laboratories and raw material distributors across Europe, North America, Southeast Asia and Middle East.
- Flexible Order Threshold & Fast Delivery Cycle
Low minimum order support for laboratory small trials; spot inventory goods deliver within 3–7 working days after deposit confirmation, no long production waiting for sample & small bulk orders.
- Full Set Customs Clearance Export Documents
We provide complete official files including COA, MSDS, TDS, ISO/FSSC22000/Kosher/Halal certification, commercial invoice, packing list for smooth customs clearance in all importing countries.
- 24/7 Free Professional Formulation Technical Support
Our cosmetic formulator team offers free dosage matching guide, compatibility test suggestion, formula optimization consultation, online technical after-sales service all day long.
- Free Lab Test Sample Support
Customers can apply 10g–100g free test samples for laboratory efficacy verification, only responsible for international shipping cost.
-
Customizable Packaging Solution
Support 1kg vacuum aluminum foil bag small package for brand lab use, 25kg fiber drum bulk industrial packaging; pallet loading service for sea & air bulk shipment.
OEM & Custom Service
- Private Label Custom Packaging
Custom printed aluminum foil bags, outer carton labels, product specification leaflets with buyer's brand logo, product introduction text and brand color scheme, supporting small batch packaging customization.
- Formula Joint Development Cooperation
Co-develop targeted ergothioneine compound active raw materials mixed with tranexamic acid, astaxanthin, resveratrol and other antioxidants according to buyer's finished product positioning, exclusive compound formula supply service.
- Customized Purity Specification Production
Custom adjust fermentation & purification process to produce customized purity grades (98% / 99% HPLC) to match different market price and efficacy demands.
- One-Stop Raw Material Matching Supply
Support combined shipment with our full series cosmetic raw materials (plant extracts, amino acids, vitamins, emollients, brightening actives), save separate international shipping cost for buyers.
- Customized Export Trade Terms
Flexible trade cooperation terms including FOB Xi'an, CIF main global ports, DHL/FedEx DDP door-to-door delivery, air freight airport-to-airport, sea freight port-to-port service, match buyer's international logistics demand.

Delivery and Shipping Service

Storage: Store in a dry, cool, and well-ventilated place.
Packaging: 1 kg/bag, 25 kg/drum
Delivery Time: 7 days after order placement
1.Express Delivery
3-5 days for shipments under 100 kg
Door-to-door service
2.Ocean Freight
Over 300 kg: Approximately 30 days. Port-to-port service requires a professional customs clearance agent.
3.Air Freight
100kg-1000kg, 5-7 days
Airport-to-airport service, requires a professional customs clearance agent

Frequently Asked Questions
Q1: What is the difference between your fermented ergothioneine and chemically synthesized EGT on the cosmetic market?
A: Our product is 100% extracted from fermented natural edible golden mushrooms, without toxic chemical synthesis raw materials and heavy catalyst residues; synthetic EGT often contains trace organic solvent residues, cannot pass strict EU cosmetic ingredient detection. Fermented EGT also retains better cell absorption activity for long-term skincare efficacy.
Q2: How long is the shelf life after opening the sealed ergothioneine package?
A: After opening the vacuum aluminum bag, seal tightly and store under 4℃ dark dry environment, the activity can remain stable for 6 months; long-term exposed to air and high temperature will gradually reduce antioxidant efficacy, we recommend sub-packaging into small sealed vials after opening.
Q3: Can ergothioneine be mixed with Vitamin C, retinol and other active ingredients in one formula?
A: Yes, our EGT owns wide pH compatibility and thermal stability, it can synergistically enhance antioxidant capacity with Vitamin C, hyaluronic acid, tranexamic acid and retinol, and reduce the irritation risk of retinol & high-concentration VC to sensitive skin. We provide free compound formula matching advice upon request.
Q4: Does ergothioneine powder cause skin irritation or allergic sensitization for topical skincare use?
A: Standard human skin irritation and sensitization clinical tests prove our cosmetic-grade EGT has mild non-irritating property; the GHS label only marks slight eye & respiratory irritation risks during raw material powder operation, finished skincare products with 0.05%-1% addition will not trigger skin allergy for normal and sensitive skin crowds.
Q5: What documents do you supply for cosmetic ingredient registration in EU & USA?
A: We provide full registration supporting files: HPLC COA, full-component MSDS, TDS, FDA GRAS certification file, EFSA novel food notification document, China IECIC listing certificate, Kosher, Halal, ISO9001 & FSSC22000 certification, which meet CPNP, FDA cosmetic raw material filing requirements.
Q6: What is the minimum order quantity for samples and formal bulk orders respectively?
A: Sample test MOQ is 500g (free 10–100g samples available); formal bulk order minimum quantity is 1kg, mass industrial production orders support 25kg fiber drum whole pallet wholesale with preferential unit price.
Q7: What delivery methods can I choose for bulk ergothioneine powder shipment? How long is the transit time?
A: Three mainstream logistics solutions: 1) DHL/FedEx express for goods under 100kg, door-to-door delivery within 3–5 working days; 2) Air freight for 100kg–1000kg goods, airport-to-airport transit time 5–7 days; 3) Sea freight for over 300kg bulk cargo, port-to-port delivery around 30 days.
Q8: Is this ergothioneine raw material allowed to be used in sunscreens and medical beauty repair products?
A: Fully permitted. It is officially listed in China IECIC cosmetic raw material catalog, approved as safe antioxidant active for sunscreen, post-laser medical beauty repair essence and sensitive barrier repair skincare, many professional medical beauty brands adopt our 99% high-purity EGT as core anti-photoaging ingredient.

Send inquiry or contact us to get free sample, and learn more details about it.
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