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98% Cosmetic Grade Phloretin Powder CAS 60-82-2 | Dowell Ingredients

INCI Name: Phloretin
CAS No: 60-82-2
EC No: 200-488-7
Molecular Formula: C₁₅H₁₄O₅
Molecular Weight: 274.27
Source: Extracted from apple peel (Malus domestica)

Description

Product Introduction of Phloretin Powder

 

Phloretin is a natural dihydrochalcone flavonoid extracted from apple peel (Malus domestica), with INCI name Phloretin, CAS No.60-82-2 and EC No.200-488-7. Our cosmetic-grade phloretin powder reaches 98% minimum purity tested by HPLC, presented as uniform white crystalline powder that meets global cosmetic manufacturing standards for brightening, anti-aging, oil control and after-sun repair formulations. Different from common whitening actives, phloretin works via multi-path skin care mechanisms: melanin inhibition, antioxidant, anti-inflammation, transdermal penetration booster and sebum regulation. It is widely recognized by cosmetic formulators for its mild, non-irritating and stable performance within pH 5.0–7.0 formulation systems.

  1. Melanin Regulation: Competitive inhibitor of tyrosinase, blocking the conversion of tyrosine to melanin precursors, reducing hyperpigmentation and uneven tone.
  2. Antioxidant Action: Donates hydrogen atoms to neutralize ROS; upregulates SOD and inhibits MMP‑1/elastase to preserve collagen and elasticity.
  3. Anti‑Inflammatory Effect: Downregulates TNF‑α, IL‑6, and NF‑κB signaling to relieve redness and support barrier recovery.
  4. Synergistic Enhancement: Improves transdermal delivery of vitamin C, ferulic acid, and other actives to boost formulation efficacy.
  5. Sebum Control: Modulates glucose uptake in sebocytes to reduce excess oil production.
Cosmetic Grade Phloretin Powder White Crystalline High Purity 98%
Product Specification

 

Strict quality control standard with full heavy metal and microbial inspection, stable batch consistency for large-batch cosmetic production.

Item Standard
Assay (HPLC) ≥98.0%
Appearance White crystalline powder
Particle Size 98% pass 80 mesh
Loss on Drying ≤1.0%
Ash Content ≤1.0%
Heavy Metals ≤10 ppm; Pb ≤1 ppm; As ≤1 ppm
Total Plate Count ≤1000 cfu/g; no pathogens
Solubility Soluble in ethanol, 1,3‑butanediol; insoluble in water
Recommended pH 5.0–7.0
Shelf Life 24 months (sealed, cool dry storage)

 

Main Skin Care Functions & Biochemical Mechanisms

 

1. Melanin Inhibition & Skin Brightening

Competitive tyrosinase inhibitor blocks tyrosine-to-melanin conversion, effectively fade post-inflammatory hyperpigmentation, dark spots and uneven skin tone, ideal for brightening serums and spot essence.

2. Powerful Antioxidant & Anti-Aging

Donates hydrogen atoms to neutralize ROS free radicals; upregulates SOD activity and inhibits MMP‑1 & elastase degradation, protect collagen, reduce fine lines and maintain skin elasticity.

3. Anti-Inflammatory & Skin Barrier Repair

Downregulate TNF‑α, IL‑6 and NF‑κB signaling pathways, relieve facial redness, soothe sensitive skin and accelerate damaged skin barrier recovery for after-sun and sensitive skincare products.

4.Synergistic Transdermal Booster

Significantly improve transdermal delivery efficiency of vitamin C, ferulic acid and other active ingredients, strengthen overall formulation efficacy when compounded with VC serum.

5.Sebum Control for Oily & Acne Skin

Modulate glucose uptake of sebocytes to restrain excessive sebum secretion, perfect for oil-control gel, acne cleanser and matte skincare formulas.

 

Safety Profile & Global Compliance

 

  • Listed in China IECIC (2021) No. 02548, legal for cosmetic manufacturing;
  • 3D human skin model test: non-irritating, no phototoxicity & skin sensitization risk;
  • Standard toxicology tests: no genotoxicity or carcinogenicity;
  • Safe recommended dosage: 0.3–2.0% for leave-on & rinse-off cosmetic products;
  • Manufacturing certified with GMP, ISO9001, ISO22716;
  • Support full documents: COA, MSDS, microbial report, heavy metal test, stability data, 3D irritation report;
  • Certifications available: Halal, Kosher, Vegan, Cruelty-Free, meets EU, US, China cosmetic regulations.

Notice: Phloretin powder is only for cosmetic raw material production, oral use forbidden; avoid eye contact, incompatible with strong acid or alkaline formula systems.

 

Recommended Application & Addition Dosage in Cosmetics

 

 

  • Skin Brightening Spot Serum: 0.5–2.0% - fade dark spots & post-acne pigmentation
  • Anti-Aging Firming Cream & Lotion: 0.3–1.5% - reduce fine lines, lift skin firmness
  • After-Sun Soothing Products: 0.5–1.0% - relieve sun redness & oxidative skin damage
  • Oil-Control Gel & Acne Skincare: 0.5–1.2% - control excess sebum for oily acne-prone skin

 

 

Certifications & Documents

 

  • GMP, ISO9001, ISO22716

  • COA, MSDS, Microbial Report, Heavy Metal Test

  • Halal, Kosher, Vegan, Cruelty‑Free

  • 3D Skin Irritation Report, Stability Data

 

Why Choose Dowell Phloretin Powder Supplier

 

  1. Stable high purity: ≥98% HPLC phloretin, consistent batch-to-batch quality control;
  2. Strict safety inspection: full heavy metal & microbial testing, zero pathogenic bacteria;
  3. Professional technical support: custom specification, formulation guidance, stability test data;
  4. Global regulatory compliance: match EU, USA, China cosmetic ingredient standards;
  5. Large-scale factory production, stable stock & on-time delivery;
  6. Flexible packaging: 1kg aluminum foil bag, 25kg fiber drum; free sample support for formula test.

 

 

Packaging, Storage & Delivery Terms

1kg foil bag packaging of phloretin cosmetic raw material for skincare formulation

01.Packaging and service

Storage: Store in a dry, cool, and well-ventilated place.

Packaging: 1 kg/bag, 25 kg/drum

Delivery Time: 7 days after order placement

02.Delivery Methods

1.Express Delivery
3-5 days for shipments under 100 kg
Door-to-door service

2.Ocean Freight
Over 300 kg: Approximately 30 days. Port-to-port service requires a professional customs clearance agent.

3.Air Freight
100kg-1000kg, 5-7 days
Airport-to-airport service, requires a professional customs clearance agent

25kg fiber drum bulk package factory supply phloretin powder CAS 60-82-2

Frequently Asked Question

 

Q1: What is the recommended addition dosage of phloretin powder in cosmetics?

A1: The safe and effective concentration range is 0.3% to 2.0% for all cosmetic leave-on and rinse-off products.

Q2: Is phloretin soluble in water?

A2: No, phloretin powder is insoluble in water, soluble in ethanol and 1,3‑butanediol and other cosmetic polyol solvents.

Q3: What pH environment keeps phloretin stable?

A3: Stable within pH 5.0–7.0, avoid strong acid or strong alkaline formulas to prevent activity loss.

Q4: Can phloretin be compounded with vitamin C?

A4: Yes, phloretin can boost vitamin C and ferulic acid transdermal absorption, improve formula stability and brightening efficacy, classic VC whitening compound matching ingredient.

Q5: What certifications can you provide for customs clearance?

A5: We supply COA, MSDS, microbial test report, heavy metal inspection report, Halal, Kosher, Vegan certificate, GMP & ISO qualification files. 

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