Product Overview
Taxifolin, also known as Dihydroquercetin, is a natural dihydroflavonol flavonoid extracted from Dahurian Larch wood, widely recognized as a premium pharmaceutical intermediate, functional food additive and cosmetic active ingredient. As a core bioactive raw material, it owns superior free radical scavenging, anti-inflammatory, anti-fibrotic and liver-protecting bioactivities, widely adopted in pharmaceutical synthesis, health supplement formulation and personal care production.
Xi'an Dowell Healthy produces standardized Taxifolin with HPLC purity 90%, 95%, 98%, fully compliant with ISO9001, FSSC22000, Halal, Kosher and Non-GMO certifications. Our strict laboratory quality control system ensures stable batch consistency, low heavy metal and solvent residue, suitable for high-end pharmaceutical intermediate formula development.
Core Bioactive Mechanism
1. Powerful Antioxidant & Free Radical Scavenger
Taxifolin's special polyphenol structure enables it to neutralize DPPH, ABTS, hydroxyl free radicals effectively, activate Nrf2 antioxidant pathway, chelate metal ions to block oxidative stress chain reaction. Its antioxidant capacity exceeds many common flavonoids, serving as key intermediate for anti-aging, liver-protecting pharmaceutical preparations.
2. Anti-Tyrosinase & Collagenase Inhibitory Activity
Significantly restrain tyrosinase and collagenase activity (IC50=193.3μM), prevent collagen degradation and melanin deposition, widely used as whitening, anti-aging cosmetic intermediate and skin protection drug raw material.
3. Anti-Inflammatory & Anti-Fibrotic Effect
Inhibit TNF-α, IL-6 inflammatory factor release, block fibrosis signal pathway, applied as intermediate for anti-fibrosis, cardiovascular auxiliary pharmaceutical formulations.
4. Hepatoprotective & Lipid-Regulating Function
Reduce liver oxidative damage, suppress HMG-CoA reductase to lower cholesterol synthesis, core raw material for liver care and lipid-lowering health drug intermediates.
5. Low Toxicity & High Safety
Natural plant-derived, non-genotoxic, EFSA approved novel food ingredient, safe for long-term oral formulation development, no obvious side effects compared with quercetin.
Multi-Grade Application Scenarios
- Pharmaceutical Intermediate
Synthetic raw material for oral liver-protecting capsules, anti-fibrosis tablets, cardiovascular auxiliary medicines
Research intermediate for anti-inflammatory, anti-tumor new drug pre-clinical trials
Active intermediate for topical skin repair pharmaceutical ointments
- Dietary Supplement Raw Material
Antioxidant soft capsule, anti-aging powder, cardiovascular support solid drink; EU novel food certified, allowable addition in beverage, yogurt, chocolate confectionery
- Cosmetic Personal Care Raw Material
Anti-oxidation essence, whitening serum, anti-wrinkle cream, sun care products; Natural anti-irritant additive for sensitive skin care formulations
- Food & Feed Additive
Natural food antioxidant preservative, pet nutrition feed additive for anti-oxidation support
Our Production & Quality Advantages
1. Full Certification System
Our Taxifolin series pass ISO9001 Quality Management, FSSC22000 Food Safety, Non-GMO, Halal, Kosher certification, all batches attached COA, SDS, HPLC test report.
2. Strict Quality Assurance Control
Whole production line closed GMP standard, raw material larch screening → ethanol extraction → vacuum concentration → crystallization → low-temperature drying → sterile crushing → metal detection, heavy metal, pesticide residue, microbial full inspection before delivery.
3. Customized OEM Service
Support customized purity specification, fine mesh powder, small package trial order, large bulk industrial packaging, private label formulation matching for pharmaceutical factory, cosmetic brand, supplement manufacturer.
4. Stable Supply & Fast Delivery
Independent extraction factory in Xi'an, annual output over 100 tons Taxifolin, spot stock for regular specifications, global door-to-door logistics support, fast response sales team within 4 working hours.
5. Free Sample Support
0.1g-10g free test samples for lab verification, buyers only undertake freight cost.
Packaging & Shipment
- Lab sample: 10g, 100g aluminum foil vacuum bag
- Industrial bulk: 25kg fiber drum with double PE inner bag
- Sea FOB shipping for large batch orders, air express for small trial samples
1.Express Delivery
3-5 days for shipments under 100 kg
Door-to-door service
2.Ocean Freight
Over 300 kg: Approximately 30 days. Port-to-port service requires a professional customs clearance agent.
3.Air Freight
100kg-1000kg, 5-7 days
Airport-to-airport service, requires a professional customs clearance agent
Frequently Asked Questions
Q1: What purity Taxifolin is suitable for pharmaceutical intermediate?
A: For pharmaceutical synthesis and oral medicine formulation, 98% HPLC purity grade is the most mainstream choice; 90%/95% grade for food supplement and cosmetic raw material.
Q2: Can you provide customized COA and lab test data?
A: Yes, every batch comes with complete Certificate of Analysis, HPLC chromatogram, heavy metal test sheet, SDS safety data sheet, third-party inspection report available on demand.
Q3: Is Taxifolin natural plant extracted or synthetic?
A: Dowell Taxifolin is 100% natural extraction from wild Dahurian Larch wood, no chemical synthetic raw material, fully compliant with clean label requirement.
Q4: What is the minimum order quantity?
A: Sample order MOQ 10g; bulk industrial order MOQ 1kg, 25kg drum for large factory procurement.
Q5: Does your Taxifolin meet international pharmaceutical grade impurity standards?
A: Absolutely. Our pharmaceutical-grade 98% Taxifolin strictly controls residual solvents, heavy metals (Pb, As, Cd, Hg) and microbial indicators, fully complying with USP, EP and FCC standards. Zero harmful impurity residue, perfectly suitable for high-standard pharmaceutical intermediate synthesis and clinical formulation research.
Q6: What is your batch consistency control standard for Taxifolin?
A: We adopt fixed raw material origin, standardized low-temperature extraction and sterile production process. The purity deviation of different batches is controlled within ±0.5%, with stable color, solubility and bioactivity. It effectively avoids formulation failure risks for long-term pharmaceutical and cosmetic mass production.
Q7: Can you provide export customs clearance documents for global shipment?
A: Yes. We support full set of export documents including commercial invoice, packing list, bill of lading, origin certificate, health certificate and customs declaration form. All documents are compliant with EU, Southeast Asia, Middle East and American market import regulations, helping customers clear customs smoothly.
Q8: What is the difference between Taxifolin and Quercetin in pharmaceutical application?
A: Compared with Quercetin, Taxifolin has higher water solubility, better thermal stability and lower cytotoxicity. It will not produce oxidative degradation under high-temperature pharmaceutical synthesis process, and has stronger liver protection and anti-fibrotic activity. It is a safer and more efficient alternative intermediate for high-end pharmaceutical and high-standard health products.
Fixed Disclaimer
Send inquiry or contact us to get free sample, and learn more details about it.
Hot Tags: taxifolin dihydroquercetin cas 480-18-2 | high purity pharmaceutical intermediate supplier - xi'an dowell healthy, China taxifolin dihydroquercetin cas 480-18-2 | high purity pharmaceutical intermediate supplier - xi'an dowell healthy manufacturers, suppliers, factory
