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Coated L(+)‑Choline Bitartrate

Product Name: L+ Choline Bitartrate Coated
INCI Name: Choline Bitartrate
Chemical Name: (2-hydroxyethyl)trimethylammonium-L-(+)-tartrate salt
CAS No.: 87-67-2
EINECS: 201-763-4
FAO/WHO INS: 1001(v)
Molecular Formula: C₉H₁₉NO₇
Molecular Weight: 253.25

Description

Product Description

 

Coated L(+)‑Choline Bitartrate is a micro‑encapsulated choline nutrient salt manufactured via advanced particle coating technology. Unlike conventional uncoated choline bitartrate, the protective outer shell greatly cuts down moisture absorption, suppresses unpleasant trimethylamine‑related odor generation during long‑term storage, and dramatically improves powder flow performance for industrial formulation workflows.

Choline serves as a fundamental essential nutrient for human and animal physiology. It acts as building units for phosphatidylcholine that constructs cell membrane architecture, and acetylcholine, the key neurotransmitter supporting neural signal transmission. Within metabolic pathways, choline delivers methyl groups for one‑carbon metabolism, facilitates lipoprotein assembly to boost liver lipid export, and mitigates excess fat buildup inside hepatic tissues.

Thanks to surface modification, this coated grade performs excellently for dry mixing, tablet direct compression, and feed premix production. It avoids common processing troubles such as powder caking, sticking, and tablet capping caused by high hygroscopicity of native choline bitartrate. The product keeps high water‑soluble property while gaining better handling stability for solid‑form finished goods.

 

Product Specification

 

Item Standard Value
Appearance White crystalline powder
Odor Odorless or faint characteristic odor
Melting Point 151–153 °C
Bulk Density 0.70–0.85 g/mL
Water Solubility (25 °C) 122 g / 100 g water
Assay (Dry Basis) ≥98.0%
pH (10% Aqueous Solution) 3.0–4.0
Loss on Drying ≤0.5%
Residue on Ignition ≤0.1%
Heavy Metals (Pb, As, Cd, Hg) Complies with food‑grade limits

 

Safety Profile

 

Choline Bitartrate Coated is recognized as safe for use in foods, supplements, and animal feed under intended usage conditions.

  • Oral LD₅₀ (choline basis): approx. 200–400 g in humans; acute toxicity is low.
  • At recommended dosages, adverse effects are uncommon; high intake may cause mild gastrointestinal upset or fishy odor due to trimethylamine metabolism.

  • May cause slight eye, skin, or respiratory irritation; avoid inhalation and direct contact.

  • Not classified as a hazardous material for transport; incompatible with strong oxidizing agents.

  • Pregnant, lactating, or medically compromised persons should consult a professional before use in human formulations.

 

Applications

 

Human Nutraceutical & Food Sector

  • Direct‑compress tablets, hard‑shell capsules, multi‑ingredient powder blends for dietary supplement brands
  • Fortified functional food, nutrient‑enhanced beverage formulations
  • Infant nutrition raw materials complying with local food safety legislations

Animal Nutrition & Feed Industry

Premix additive for swine, poultry and aquaculture feed formulas

Optimizes hepatic lipid metabolism and maintains animal liver health; follow regional feed additive dosage restrictions.

Important Restricted Usage

Not permitted for injectable preparations, non‑authorized pharmaceutical therapeutic products, or high‑dose clinical formulations without formal regulatory approvals.

 

Why Choose Us

 

  • Stable Coating Technology: We adopt mature micro‑encapsulation craft to achieve balanced moisture resistance and active substance release; customized coating thickness and particle grading are available for your production lines.
  • Full‑Set Compliance Documentation: Every batch can provide COA, MSDS, Halal, Kosher, ISO supporting documents. Non‑GMO, allergen‑free, non‑irradiated raw material guarantee, anti‑doping compliant for sports nutrition markets.
  • Strict In‑house Quality Control: All raw materials and finished goods go through multi‑stage lab testing before shipment, heavy‑metal & microbial inspection included, to secure consistent batch‑to‑batch quality.
  • Flexible Packaging & Global Logistics: Multiple packaging options for lab trial and bulk commercial orders. Multiple shipping solutions for air, sea and express delivery to cover different weight‑range shipments worldwide.
  • Technical Application Support: Our technical team offers formulation advice for tablet pressing, dry blending and feed premixing to help you resolve common processing obstacles.
  • Sample Service: Free product samples are accessible for your lab evaluation before bulk purchase.

 

OEM Service

 

We deliver flexible OEM & custom manufacturing service for coated L(+)‑Choline Bitartrate raw material:

  • Custom coating ratio: Adjust shell proportion to match your requirements on anti‑hygroscopic performance and odor‑masking effect.
  • Custom particle‑size distribution: Tune particle mesh range to fit your mixing equipment and tablet compression process.
  • Custom package service: Support private‑label inner bags / drum packaging for bulk ingredients.
  • Batch‑size flexibility: Support small trial batches and large‑volume commercial mass production.
  • Documentation customization: Provide formal documents aligned with your target market regulatory requirements.

OEM Service

Delivery and Shipping Service

Modern warehouse automated conveyor system for coated choline bitartrate bulk goods packaging and handling

01.

Packaging and service

Storage: Store in a dry, cool, and well-ventilated place.

Packaging: 1 kg/bag, 25 kg/drum

Delivery Time: 7 days after order placement

02.

Delivery Methods

1.Express Delivery
3-5 days for shipments under 100 kg
Door-to-door service

2.Ocean Freight
Over 300 kg: Approximately 30 days. Port-to-port service requires a professional customs clearance agent.

3.Air Freight
100kg-1000kg, 5-7 days
Airport-to-airport service, requires a professional customs clearance agent

Global logistics solution for bulk nutritional raw materials: air freight, sea freight and ground transportation for coated choline bitartrate shipment

 

Everything You Need to Know

 

Q1: How does micro‑coated choline bitartrate differ from standard uncoated choline bitartrate in practical production?

A: Uncoated choline bitartrate absorbs moisture easily and tends to cake, releasing fishy odor upon storage. The micro‑coated variant minimizes moisture uptake, restrains odor development, improves powder flow, and brings much better adaptability for tablet compression and feed premixing work flows.

Q2: Can this coated choline bitartrate be applied for direct compression tablet production?

A: Yes. Optimized flowability and anti‑sticking feature reduce capping and sticking defects during direct compression, perfectly matching dry‑tablet manufacturing processes.

Q3: What is the shelf‑life condition for coated choline bitartrate?

A: Keep sealed in cool, dry and well‑ventilated storage environment, avoid direct sunlight and high humidity. Under proper storage condition, shelf‑life reaches 24 months.

Q4: Can you adjust particle size and coating layer thickness according to customer formulation needs?

A: Sure. Our R&D workshop supports tailored coating proportion and particle‑size distribution. Please provide your mixing or pressing equipment requirements so we can recommend suitable specs.

Q5: Is coated choline bitartrate Halal & Kosher certified?

A: Yes. Halal and Kosher certificates are available upon request. This material is also non‑GMO, allergen‑free and anti‑doping compliant.

Q6: What possible adverse reactions may appear for human oral intake of choline bitartrate?

A: Under recommended dosage, adverse reactions rarely occur. Excessive intake may trigger mild gastrointestinal discomfort or fishy odor from trimethylamine metabolism. Pregnant, lactating population or people with underlying medical conditions should consult health professionals before developing human‑use finished products.

Q7: Which shipping options are available for coated choline bitartrate bulk orders?

A: We provide 3 shipping modes: international express for small‑weight orders, air freight for medium bulk cargo, and ocean freight for heavy‑weight large shipments. Relevant customs documents will be supplied.

Q8: Could I get free samples for lab testing?

A: Yes, free samples are available for quality & formulation validation. Please send inquiry with your contact information and sample quantity requirement, our team will arrange sample delivery for you.

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