Products Description
Policosanol is a complex mixture of long-chain saturated aliphatic primary alcohols naturally isolated from sugarcane wax, rice bran wax and beeswax, with 1-Octacosanol as the dominant active constituent, accompanied by triacontanol, hexacosanol and other homologous fatty alcohols. The raw material is refined via solvent extraction, molecular distillation and recrystallization processes to remove wax impurities, pigments and macromolecular lipids, presenting stable chemical structure and standardized active content. It modulates lipid metabolism by regulating hepatic cholesterol synthesis and lipoprotein distribution, enhances cellular energy metabolism via mitochondrial pathway activation, improves insulin sensitivity through peripheral glucose uptake regulation, and alleviates vascular oxidative stress by scavenging free radicals. The product features thermal stability, acid-base resistance and low hygroscopicity, insoluble in water and soluble in hot organic solvents, suitable for formula integration of dietary supplements, functional foods and cosmetic raw materials.
Technical Specification
| Item | Specification |
|---|---|
| Product Name | Policosanol Octacosanol |
| INCI Name | Octacosanol |
| CAS No. | 557-61-9 |
| Molecular Formula | C₂₈H₅₈O |
| Molecular Weight | 410.76 |
| Appearance | White Crystalline Powder |
| Total Policosanol Content | 5%-95% Customizable; Octacosanol ≥98% |
| Melting Point | 75-85℃ (Standard Grade: 81-83℃) |
| Acid Value (mgKOH/g) | ≤1.5 |
| Moisture | ≤0.5% |
| Ash Content | ≤0.1% |
| Lead (Pb) | ≤0.1mg/kg |
| Arsenic (As) | ≤0.3mg/kg |
| Mercury (Hg) | ≤0.01mg/kg |
| Cadmium (Cd) | ≤0.2mg/kg |
| Total Plate Count | ≤5×10⁴ CFU/g |
| Mold & Yeast | Mold ≤50 CFU/g; Yeast ≤20 CFU/g |
| Coliform Group | ≤100 MPN/100g |
| Pathogenic Bacteria | Negative (Not Detected) |
| Solubility | Insoluble in Water; Soluble in Hot Ethanol, Chloroform, Benzene |
Safety Profile
- Acute Toxicity: Oral LD₅₀ >18000mg/kg in mice, classified as practically non-toxic with extremely high safety margin.
- Genotoxicity: Ames test, mouse bone marrow micronucleus test and sperm aberration test show no genotoxic potential.
- Side Effects: Recommended daily dose 5-40mg, mild occasional gastrointestinal discomfort (nausea, heartburn) incidence <3%; insomnia incidence <1%, no severe adverse reactions recorded in long-term clinical trials.
- Applicable Crowd Restriction: Pregnant, lactating women and patients taking anticoagulant/antiplatelet drugs need professional medical guidance before use.
- Stability: Stable under normal temperature, light and acid-base environment, no degradation within shelf life when sealed properly.
- Safety Certificates: Available COA, MSDS, Heavy Metal Test Report, Microbial Test Report, Halal/Kosher Optional (support certificate document & picture uploading)
Applications
- Dietary Supplements：Only for capsule, tablet and softgel formulations targeting lipid regulation, blood sugar balance and endurance improvement; not allowed for intravenous injection or high-dose concentrated preparations.
- Functional Foods：Allowed to add in health bars, nutritional shakes and solid beverages with limited dosage; prohibited for infant food, baby complementary food and special medical food without regulatory approval.
- Cosmetic Raw Materials：Used only in skin care products for antioxidant and anti-oxidative stress efficacy; not applicable to lip care, eye surrounding and sensitive skin high-dose formulations.
- Sports Nutrition：Applied in energy supplement powder and endurance formula for athletes; strictly follow regional dosage standards for sports nutritional products.
- Prohibited Application: Not for drug raw materials, veterinary drugs and agricultural additives without official registration.
Why Choose Us
- Raw Material Source Control: Adopt natural sugarcane wax/rice bran wax raw materials, fixed origin supply, no mixed adulteration, stable batch-to-batch consistency.
- Customized Specification Support: Provide 5%-95% policosanol custom content, support OEM particle size, fineness and formula customization for different industries.
- Full Qualification & Test Reports: Each batch attached with COA, MSDS, microbial and heavy metal test reports; Halal, Kosher certificates can be applied to meet global market access.
- Factory Direct Supply & Fast Delivery: Independent production workshop, large inventory spot supply; 7-day delivery for sample and bulk order, support air/sea/express multi-channel logistics.
- Strict Quality System: Implement GMP production standard, full-process quality inspection, heavy metal and microbial strict compliance with EU and international food additive standards.
- Professional Technical Support: Provide formula guidance, application dosage suggestion and regulatory document consulting for global customers.
delivery and shipping service
Storage: Store in a dry, cool, and well-ventilated place.
Packaging: 1 kg/bag, 25 kg/drum
Delivery Time: 7 days after order placement
1.Express Delivery
3-5 days for shipments under 100 kg
Door-to-door service
2.Ocean Freight
Over 300 kg: Approximately 30 days. Port-to-port service requires a professional customs clearance agent.
3.Air Freight
100kg-1000kg, 5-7 days
Airport-to-airport service, requires a professional customs clearance agent
Frequently Asked Questions
Can Policosanol lower cholesterol safely?
-
A: Yes, it regulates LDL and HDL levels via modulating hepatic lipid synthesis, with low side effects and high safety at recommended doses.
Will Policosanol cause blood sugar elevation?
-
A: No, it improves insulin sensitivity to stabilize blood glucose and does not trigger blood sugar rise.
What is the solubility of Policosanol Octacosanol?
-
A: It is insoluble in water, slightly soluble in hot ethanol, and soluble in organic solvents like chloroform and benzene.
What purity grades can you supply?
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A: We provide 5%-95% total policosanol, and 98% high-purity octacosanol, support custom specification.
What safety certificates can you provide?
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A: We can supply COA, MSDS, heavy metal & microbial test reports, Halal and Kosher certificates for optional application.
Send inquiry or contact us to get free sample, and learn more details about it.
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