Products Description
Horny Goat Weed Extract Powder is a standardized botanical extract derived from the leaves of Epimedium brevicornu. Its primary bioactive constituent is icariin, a prenylated flavonoid glycoside.
Mechanism of Action
- Icariin acts as a selective PDE5 inhibitor, supporting cyclic guanosine monophosphate (cGMP) accumulation and promoting smooth muscle relaxation in vascular tissue.
- It modulates nitric oxide (NO) signaling to enhance endothelial function and peripheral blood flow.
- Icariin exhibits phytoestrogen‑like activity via ERα‑mediated pathways, supporting osteoblast differentiation, bone mineralization, and bone remodeling balance.
- It suppresses osteoclastogenesis and bone resorption while exerting antioxidant and anti‑inflammatory effects at the cellular level.
- The extract supports neuroprotective and mitochondrial stabilizing functions through attenuation of oxidative stress and inflammatory cascades.
This product is manufactured using low‑temperature vacuum concentration and constant‑temperature extraction to minimize thermal degradation, ensuring high icariin retention and consistent biological activity.
Technical Specification
| Item | Specification | Test Method |
|---|---|---|
| Icariin | 5% – 98% | HPLC |
| Appearance | Brown‑yellow to light‑yellow fine powder | Visual |
| Bulk Density | 50 – 60 g/100 mL | USP <616> |
| Particle Size | 95% – 99% pass 80‑mesh | Sieve Analysis |
| Loss on Drying | ≤ 1.0% | Gravimetry |
| Ash Content | ≤ 1.0% | Gravimetry |
| Total Heavy Metals | ≤ 10 ppm | ICP‑MS |
| Lead (Pb) | ≤ 2 ppm | ICP‑MS |
| Cadmium (Cd) | ≤ 1 ppm | ICP‑MS |
| Arsenic (As) | ≤ 2 ppm | ICP‑MS |
| Mercury (Hg) | ≤ 1 ppm | AFS |
| Total Plate Count | ≤ 1000 CFU/g | USP <61> |
| Yeast & Mold | ≤ 100 CFU/g | USP <61> |
| E. coli | Negative | USP <62> |
| Salmonella | Negative / 25 g | USP <62> |
| pH Stability | 4.0 – 8.0 | pH Meter |
| Shelf Life | 24 months (sealed, dry, dark) | Accelerated Testing |
Safety Profile
- Acute & Subchronic Toxicity: No significant acute toxicity reported at recommended use levels.
- Hepatotoxicity: No clinical evidence of liver injury linked to pure Epimedium extract.
- Genotoxicity: Non‑mutagenic in standard assays.
- Contraindicated Populations:
Pregnancy & lactation
Children < 18 years
Hormone‑sensitive cancers (breast, uterine, ovarian)
Bleeding disorders or anticoagulant therapy
Within 2 weeks prior to surgery
- Cautions:
May potentiate effects of PDE5 inhibitors (sildenafil, tadalafil).
High‑dose or prolonged use may cause tachycardia, dizziness, or gastrointestinal upset.
- Usage Limits: For industrial formulation only; not for direct consumption as finished product.
Applications
Approved for use only in the following categories:
- Dietary Supplements: Tablets, capsules, softgels, powders (adult‑only formulas).
- Functional Foods & Beverages: Fortified drinks, bars, powders (adult‑use only).
- Cosmetic Ingredients: Skin‑care formulations for mature skin (external use only).
- Nutraceutical Blends: Formulations for bone health, physical vitality, and endothelial support.
Restrictions:
Not for use in products for children, pregnancy, or lactation.
Not for injectable or pharmaceutical drug use without additional GMP/regulatory approval.
Not for use in products claiming treatment or cure of any disease.
Safety & Quality Certifications
- ISO 9001
- ISO 22000 / HACCP
- Kosher
- Halal
- Non‑GMO Project Compliant
- Allergen‑Free
- Non‑Irradiated
- Anti‑Doping Certified
- COA & MSDS available per batch
- Third‑party tested by SGS / Eurofins
Why Choose Us
- Precise StandardizationIcariin 5%–98% customizable; full HPLC traceability ensures batch‑to‑batch consistency.
- High‑Activity ExtractionLow‑temperature process preserves >90% icariin activity vs. traditional methods.
- Strict Quality ControlFull heavy metal, microbial, and solvent residual control; compliant with EU, US, and Asian food standards.
- Formulation CompatibilityStable in pH 4.0–8.0; compatible with water, alcohol, and oil‑based systems.
- Global Logistics Support25 kg fiber drums; vacuum aluminum foil inner packaging; 24‑month shelf life.
- Full DocumentationCOA, MSDS, specs, and certificates provided for customs and regulatory clearance.
Frequently Asked Questions
Is this product GMO‑free, allergen‑free, and non‑irradiated?
-
Yes, fully compliant.
Can I get a sample before ordering?
-
Samples available upon request; shipping cost applies.
Is your product tested for heavy metals and microbes?
-
Yes, full testing per international standards; COA included.
Do you support OEM or private labeling?
-
We supply raw material only; no finished product labeling.
What is the purity range of your extract?
-
We offer Icariin 5%, 10%, 20%, 40%, 60%, 98% customizable.
Delivery and Shipping Service
Storage: Store in a dry, cool, and well-ventilated place.
Packaging: 1 kg/bag, 25 kg/drum
Delivery Time: 7 days after order placement
1.Express Delivery
3-5 days for shipments under 100 kg
Door-to-door service
2.Ocean Freight
Over 300 kg: Approximately 30 days. Port-to-port service requires a professional customs clearance agent.
3.Air Freight
100kg-1000kg, 5-7 days
Airport-to-airport service, requires a professional customs clearance agent
Send inquiry or contact us to get free sample, and learn more details about it.
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