What Is Cordycep Acid Powder (D-Mannitol)
Cordycep Acid Powder is a standardized natural active ingredient extracted from Cordyceps militaris fruit bodies via submerged fermentation, water extraction, purification, and spray‑drying. Its primary constituent is D‑mannitol (cordycepic acid), a polyol compound with well‑documented biological activities.
Mechanisms of Action
- D‑mannitol acts as an osmoprotectant, free‑radical scavenger, and anti‑inflammatory modulator via inhibition of pro‑inflammatory pathways (e.g., MAPK) and reduction of TNF‑α, IL‑6, and oxidative stress.
- Polysaccharides & β‑glucans support immune homeostasis via pattern recognition receptors and gut‑associated lymphoid tissue signaling.
- Adenosine & cordycepin modulate energy metabolism, mitochondrial function, and nucleoside‑mediated cellular signaling.
- The material is chemically stable at processing temperatures ≤80°C, with consistent solubility and bioactivity retention.
Key Bioactive Ingredients & HPLC Test Specifications
| Item | Standard Value | Test Method |
|---|---|---|
| Product Name | Cordycep Acid Powder / Cordyceps Militaris Extract | - |
| INCI Name | CORDYCEPS MILITARIS EXTRACT; D‑MANNITOL | - |
| CAS No. | D‑Mannitol: 69‑65‑8; Cordycepin: 73‑03‑0 | - |
| Part Used | Cordyceps militaris fruit body | Visual ID |
| Appearance | Yellowish‑brown fine powder | Visual |
| Cordycepic Acid (D‑Mannitol) | ≥98.0% | HPLC |
| Polysaccharides | 10.0% / 30.0% / 50.0% | UV‑VIS |
| Beta‑D‑Glucans | 20.0% / 30.0% / 50.0% | UV‑VIS |
| Adenosine | 0.5% / 1.0% | HPLC |
| Cordycepin | 0.1% / 0.5% / 1.0% | HPLC |
| Loss on Drying | ≤12.0% | Gravimetry |
| Particle Size | 100% pass 80 mesh | Sieve |
| Heavy Metals | As ≤1.0 ppm; Pb ≤2.0 ppm; Cd ≤0.5 ppm; Hg ≤0.1 ppm | AAS/ICP‑MS |
| Microbial | Total Plate Count ≤1000 CFU/g; Yeast/Mold ≤100 CFU/g; Salmonella/E. coli: Negative | USP |
| Shelf Life | 2 years (cool, dry, dark) | Stability |
Safety Profile & Global Regulatory Certifications
- Toxicity Safety: Oral acute LD50 >5000mg/kg in rodent test, non-toxic under recommended dosage
- Skin & Eye Irritation: Non-irritating, non-sensitizing, passes cosmetic human patch test
- Contaminant Control: Pesticides, mycotoxins, heavy metals all meet EU ECHA & US FCC limit standards
- Population Cautions
- Pregnant & lactating women: Insufficient clinical data, not recommended
- Anticoagulant users: Caution for mild antiplatelet activity
- Diabetic patients: Monitor blood glucose when combined with hypoglycemic drugs
- Surgical patients: Stop intake 7 days before operation
- Full Global Certifications: ISO 22000, Kosher, Halal, Non-GMO, Allergen-Free, Non-Irradiated, Anti-Doping Compliant Full supporting documents: COA, MSDS, production flow chart, certification scan copies provided for customs clearance & registration
Multi-Industry Industrial Applications
Food & Beverage Grade
- Application Scenarios: Energy drinks, sports nutrition solid drinks, chewable tablets, functional granules
- Recommended Dosage in Finished Goods: 0.1%–2.0%
- Daily Maximum Intake for Human: ≤4g per person
- Restrictions: Not applicable for infant food, forbidden for injection use
Dietary Supplement Raw Material
- Form Types: Capsules, compressed tablets, bulk blend powder
- Standard Daily Dosage: 200–1000mg standardized extract / 1000–3000mg crude militaris powder
- Notes: Children under 12 years old not recommended; customers with chronic medication need medical consultation
Cosmetic & Personal Care Grade
- Formulas: Moisturizing serums, soothing facial creams, repair masks, anti-aging skincare
- Recommended Addition Ratio: 0.1%–1.0% for leave-on & rinse-off products
- Safety Tip: Avoid contact with open wounds; for external use only, do not ingest orally
Prohibited Application Scenarios
Injectable drugs, veterinary injection solutions, clinical IV liquids; cannot make medical claims of diagnosis, cure or disease treatment.
Why Choose Dowell as Your Cordycep Acid Powder Manufacturer
- Standardized High Purity Marker
Guaranteed ≥98% D-Mannitol content; every batch full HPLC & UV testing, complete marker quantification of polysaccharides, beta-glucans, adenosine and cordycepin. Stable active content without batch fluctuation.
- Large-Scale Stable Fermentation Supply
Independent submerged fermentation workshop, annual output over tons of Cordyceps militaris extract, support continuous bulk order delivery without stock shortage risk.
- Full Global Regulatory Certification Pack
ISO 22000, Kosher, Halal, Non-GMO, Anti-Doping compliant; complete COA, MSDS, pesticide & heavy metal test reports for EU, US, Southeast Asia market registration & customs clearance.
- Professional Formulation Technical Support
Our R&D team provides formula dosage guidance, stability test data, regional regulatory compliance documents, and customized spec development service for your brand products.
- Flexible Global Logistics Service
Multiple packaging options, mixed container loading support; sea, air, express multi-channel global shipping, dedicated sales follow-up whole logistics process.
- Fast Customer Response
Professional international sales team reply inquiry within 12 hours; one-stop service from sample testing, mass production to shipment document arrangement.
Certifications
ISO 22000 | Kosher | Halal | Non‑GMO | Allergen‑Free | Anti‑Doping | COA | MSDS
Bulk Packaging & Global Shipping Solutions
Storage: Store in a dry, cool, and well-ventilated place.
Packaging: 1 kg/bag, 25 kg/drum
Delivery Time: 7 days after order placement
- Express Door-to-Door (Sample & Small Bulk <100kg) Lead time: 3–5 working days; door-to-door delivery, simple customs clearance support
- Air Freight (100kg–1000kg Medium Bulk) Lead time: 5–7 working days; airport-to-airport service, provide customs clearance document set
- Ocean Freight (Over 300kg Large Container Order) Lead time: Around 30 days port-to-port; full commercial invoice, packing list, certificate file for customs agent
Frequently Asked Questions
Q1: What is the CAS number of cordycepic acid and cordycepin?
A: D-Mannitol (Cordycepic Acid): 69-65-8; Cordycepin:73-03-0. Full CAS info listed on COA for your market registration.
Q2: Is cordycep acid powder water-soluble?
A: Yes, it dissolves rapidly in cold & hot water to form transparent solution; insoluble in ethanol and oily solvents.
Q3: Can this product be used in food formulations?
A: Approved GRAS status, widely applied in global functional food and sports nutrition with safe recommended dosage.
Q4: What heavy metal limits does your product comply with?
A: Strictly follows EU & US standards: As ≤1.0 ppm, Pb ≤2.0 ppm, Cd ≤0.5 ppm, Hg ≤0.1 ppm. Heavy metal test data attached to each batch COA.
Q5: Is it suitable for cosmetic raw material?
A: Fully cosmetic-grade, non-irritating & non-sensitizing for skin care formulas; standard usage ratio 0.1–1.0%.
Q6: Can you provide customized active ingredient content?
A: Yes, we support custom D-Mannitol, polysaccharide, cordycepin specifications according to your regional formula requirements.
Q7: Can I get free sample for testing?
A: Free 10–50g samples available, buyer only bears international freight cost; sample COA sent together with goods.
Send inquiry or contact us to get free sample, and learn more details about it.
Hot Tags: Cordycep Acid Powder D-Mannitol 98% | Cordyceps Militaris Extract Supplier Dowell, China Cordycep Acid Powder D-Mannitol 98% | Cordyceps Militaris Extract Supplier Dowell manufacturers, suppliers, factory, maca extract powder health nutrition ingredient, maca extract powder wellness nutrition ingredient, maca extract powder health formulation ingredient, maca extract powder active supplement ingredient, maca extract powder herbal formulation ingredient, maca extract powder focus enhancement ingredient
