Products Description
Cordycep Acid Powder is a standardized natural active ingredient extracted from Cordyceps militaris fruit bodies via submerged fermentation, water extraction, purification, and spray‑drying. Its primary constituent is D‑mannitol (cordycepic acid), a polyol compound with well‑documented biological activities.
Mechanisms of Action
- D‑mannitol acts as an osmoprotectant, free‑radical scavenger, and anti‑inflammatory modulator via inhibition of pro‑inflammatory pathways (e.g., MAPK) and reduction of TNF‑α, IL‑6, and oxidative stress.
- Polysaccharides & β‑glucans support immune homeostasis via pattern recognition receptors and gut‑associated lymphoid tissue signaling.
- Adenosine & cordycepin modulate energy metabolism, mitochondrial function, and nucleoside‑mediated cellular signaling.
- The material is chemically stable at processing temperatures ≤80°C, with consistent solubility and bioactivity retention.

Products Description
| Item | Standard Value | Test Method |
|---|---|---|
| Product Name | Cordycep Acid Powder / Cordyceps Militaris Extract | - |
| INCI Name | CORDYCEPS MILITARIS EXTRACT; D‑MANNITOL | - |
| CAS No. | D‑Mannitol: 69‑65‑8; Cordycepin: 73‑03‑0 | - |
| Part Used | Cordyceps militaris fruit body | Visual ID |
| Appearance | Yellowish‑brown fine powder | Visual |
| Cordycepic Acid (D‑Mannitol) | ≥98.0% | HPLC |
| Polysaccharides | 10.0% / 30.0% / 50.0% | UV‑VIS |
| Beta‑D‑Glucans | 20.0% / 30.0% / 50.0% | UV‑VIS |
| Adenosine | 0.5% / 1.0% | HPLC |
| Cordycepin | 0.1% / 0.5% / 1.0% | HPLC |
| Loss on Drying | ≤12.0% | Gravimetry |
| Particle Size | 100% pass 80 mesh | Sieve |
| Heavy Metals | As ≤1.0 ppm; Pb ≤2.0 ppm; Cd ≤0.5 ppm; Hg ≤0.1 ppm | AAS/ICP‑MS |
| Microbial | Total Plate Count ≤1000 CFU/g; Yeast/Mold ≤100 CFU/g; Salmonella/E. coli: Negative | USP |
| Shelf Life | 2 years (cool, dry, dark) | Stability |
Safety Profile
- GRAS status for food applications; widely used in foods, supplements, and cosmetics.
- Acute oral LD50 >5000 mg/kg in rodents; non‑toxic under intended use levels.
- Skin & eye: Non‑irritating, non‑sensitizing in cosmetic safety assessments.
- Contaminant control: Heavy metals, pesticides, mycotoxins, and pathogens meet EU/US/FCC limits.
- Cautions:
Not recommended for pregnancy/lactation (insufficient data).
Caution with anticoagulants (mild antiplatelet potential).
Diabetics: monitor blood glucose with concurrent meds.
Discontinue ≥7 days prior to surgery.
- Certifications: ISO 22000, Kosher, Halal, Non‑GMO, Allergen‑Free, Non‑Irradiated, Anti‑Doping compliant.
Applications
Food & Beverage
- Energy drinks, sports nutrition, solid drinks, granules, chewables.
- Use level: 0.1–2.0% in finished products; max daily intake ≤4 g/person.
- Restrictions: Not for infant foods; not for injectable use.
Dietary Supplements
- Capsules, tablets, powders for immune, energy, and endurance support.
- Daily dose: 200–1000 mg extract (standardized) or 1000–3000 mg crude powder.
- Restrictions: Not for children <12 years; consult physician for chronic meds.
Cosmetics & Personal Care
- Skin protection, soothing, moisturizing serums, creams, masks.
- Use level: 0.1–1.0% in leave‑on/rinse‑off formulas.
- Restrictions: Not for oral ingestion; avoid contact with open wounds.
Prohibited Uses
- Injectable drugs, veterinary injectables, clinical IV solutions.
- Claims for diagnosis, cure, mitigation, or treatment of disease.
Why Choose Us
- Standardized precision: D‑mannitol ≥98%; full marker quantification (polysaccharides, β‑glucans, adenosine, cordycepin).
- Stable supply: Large‑scale submerged fermentation; consistent batch‑to‑batch quality.
- Certified safety: ISO, Kosher, Halal, Non‑GMO, Allergen‑Free, Anti‑Doping; full COA/MSDS available.
- Technical support: Custom specifications, formula guidance, stability data, and regulatory compliance dossiers.
- Logistics: Flexible packaging (1 kg/bag, 25 kg/drum); 7–15 day lead time; global sea/air/express shipping.
Certifications
ISO 22000 | Kosher | Halal | Non‑GMO | Allergen‑Free | Anti‑Doping | COA | MSDS
delivering and shipping service

Storage: Store in a dry, cool, and well-ventilated place.
Packaging: 1 kg/bag, 25 kg/drum
Delivery Time: 7 days after order placement
1.Express Delivery
3-5 days for shipments under 100 kg
Door-to-door service
2.Ocean Freight
Over 300 kg: Approximately 30 days. Port-to-port service requires a professional customs clearance agent.
3.Air Freight
100kg-1000kg, 5-7 days
Airport-to-airport service, requires a professional customs clearance agent

Frequently Asked Questions
What is the CAS number for cordycep acid?
-
D‑Mannitol: 69‑65‑8; Cordycepin: 73‑03‑0.
Is this powder water‑soluble?
-
Yes; cordycep acid dissolves rapidly in water to form a clear solution; insoluble in ethanol.
Is cordycep acid safe in food?
-
Yes; it is GRAS and widely used in foods, beverages, and supplements with no known toxicity at recommended levels.
What are the heavy metal limits?
-
As ≤1.0 ppm, Pb ≤2.0 ppm, Cd ≤0.5 ppm, Hg ≤0.1 ppm, complying with EU/US standards.
Can this be used in cosmetics?
-
Yes; safe for skin care, non‑irritating, non‑sensitizing; typical use level 0.1–1.0%.

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