Product Overview
Nicotinic Acid is a water-soluble pyridine derivative used in food, feed, supplement, and pharmaceutical applications.
Technical Specifications
|
Category |
Parameter |
Specification / Value |
|
Product Identification |
Product Name |
Nicotinic Acid |
|
Chemical Name |
Pyridine-3-carboxylic acid |
|
|
CAS No. |
59-67-6 |
|
|
EINECS No. |
200-441-0 |
|
|
Physical Constants |
Molecular Formula |
C₆H₅NO₂ |
|
Molecular Weight |
123.11 |
|
|
Melting Point |
234°C–238°C |
|
|
Physical Properties |
Appearance |
White to off-white crystalline powder |
|
Solubility |
Freely soluble in boiling water and ethanol; sparingly soluble in water (~15 g/L at 20°C); practically insoluble in ether |
|
|
pH Value |
3.0–4.0 (10 g/L aqueous solution, 25°C) |
|
|
Purity & Loss |
Assay (HPLC/Titration) |
≥99.0% (on dry basis) |
|
Loss on Drying |
≤0.5% |
|
|
Residue on Ignition |
≤0.1% |
|
|
Impurities Control |
Related Substances |
Any individual impurity ≤0.1%; total impurities ≤0.5% |
|
Chloride |
≤0.02% |
|
|
Sulfate |
≤0.02% |
|
|
Heavy Metals |
Total Heavy Metals |
≤10 ppm |
|
Lead (Pb) |
≤2 ppm |
|
|
Arsenic (As) |
≤1 ppm |
|
|
Mercury (Hg) |
≤0.1 ppm |
|
|
Cadmium (Cd) |
≤1 ppm |
Quality Assurance & Global Certifications
|
Standards & Certifications |
Compliance & Scope |
|
GMP Compliance |
Manufactured under current Good Manufacturing Practices with documented process controls. |
|
CEP / COS Availability |
CEP / COS documentation is available for applicable markets. |
|
ISO 9001 & 22000 |
Certified quality management and food safety systems applied across operations. |
|
FAMI-QS Certified |
Complies with European feed ingredient safety and quality requirements. |
|
Kosher & Halal |
Facility and processes are certified compliant with dietary standards. |
|
HACCP Implementation |
Critical control points applied throughout production and packaging processes. |
Manufacturing Capacity & Supply Chain
Annual Capacity
Dedicated synthesis lines support commercial-scale Nicotinic Acid production.
Cyanopyridine Sourcing
Upstream raw material sourcing supports production scheduling.
Moisture Protection
Handling protocols are used to reduce moisture exposure during transportation.
Bulk Powder Packaging
Dedicated filling lines pack technical and pharma-grade batches in moisture-barrier drums.
Crystalline Lot Traceability
Batch tracking records are maintained from production through delivery.
Redundant Synthesis Lines
Multi-line chemical reactors support production continuity.
R&D Expertise & Customization
Particle Size Milling: Micronization supports d50/d90 particle size requirements.
Catalytic Oxidation R&D: Evaluation of oxidation routes for pyridine derivative synthesis.
Flowability Optimization: Crystal habit control for powder handling during tableting.
Impurities Profiling: Chromatographic methods used to monitor process impurities.
Custom Premixes: Blending active powder with specified carrier materials.
Stability Pilot Testing: Environmental studies under defined humidity and temperature conditions.
FAQ
Q: How is cross-contamination controlled in production lines?
A: We implement validated cleaning procedures and strict production scheduling between batches.
Q: How are shipments protected in high-humidity environments?
A: Shipments may utilize moisture-barrier packaging and desiccants during transport.
Q: Are alternative bulk packaging options available?
A: Yes, we provide fiber drums and customized industrial containers based on order requirements.
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